PCOS IS EXTINCT!!!

In this episode of the Gyno Gurus Podcast, we break down the emerging concept of PMOS (Polyendocrine Metabolic Ovarian Syndrome) and why many experts believe the term “PCOS” may no longer fully capture what’s really happening in the body. We explore how genetics, epigenetics, insulin resistance, brain signaling, ovarian dysfunction, and androgen excess may all converge through different pathways to create the same clinical syndrome. From LH dysfunction and theca cell overstimulation to fasting insulin, AMH, and lipid abnormalities, this episode takes a deeper look into the true pathophysiology behind “PMOS.” Whether you’re struggling with irregular cycles, infertility, or metabolic dysfunction — understanding the why behind the condition changes everything.

 

Chapters:

00:00 PCOS is No More

05:52 Pathophysiology of PMOS

10:09 Understanding the Underlying Causes

12:13 PCOS vs PMOS, Does it Really Matter?

14:09 Markers of PMOS: LH/FSH Ratio, AMH, Fasting Insulin Levels, Dyslipidemia

19:58 Final Thoughts

 

In this episode we discuss:

• Epigenetics and fetal programming

• How PMOS may begin in the womb and brain

• LH dysregulation and ovarian signaling

• Theca cells and androgen overload

• Insulin resistance and hyperinsulinemia

• The “ovary-first” theory

• LH vs FSH ratios

• AMH and metabolic markers

• Different pathways leading to the same syndrome

 

If you enjoyed this episode, make sure to like, subscribe, and share with someone navigating PCOS/PMOS.

 

#PCOS #PMOS #InsulinResistance #Hormones #Fertility #WomensHealth #Endocrinology #Infertility #HormonalHealth #MetabolicHealth #GynoGurusPodcast